The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Jul. 05, 2022
Applicant:
Ucb Biopharma Srl, Brussels, BE;
Inventors:
Jean-Pascal Pierre Bilgischer, Brussels, BE;
Philip Jonathan Bassett, Slough, GB;
Mark Robert Pearce-Higgins, Slough, GB;
Andrew John Kenny, Slough, GB;
Assignee:
UCB BIOPHARMA SRL, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2005.12); C12P 21/00 (2005.12);
U.S. Cl.
CPC ...
C07K 16/00 (2012.12); C12P 21/00 (2012.12); C07K 2317/14 (2012.12); C07K 2317/55 (2012.12);
Abstract
The present disclosure relates to a method for the manufacture of recombinant antibody molecules comprising culturing a host cell sample transformed with an expression vector encoding a recombinant antibody molecule; adding an extraction buffer to the sample; and subjecting the sample to a heat treatment step; wherein the pH of the sample is detected after addition of the extraction buffer, and optionally adjusted, to ensure that the pH of the sample is 6 to 9 prior to the heat treatment step.