The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Apr. 14, 2022
Applicant:
Brandeis University, Waltham, MA (US);
Inventors:
Assignee:
Brandeis University, Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2005.12); A61K 9/00 (2005.12); A61K 38/17 (2005.12); A61K 48/00 (2005.12); C07K 14/00 (2005.12); C07K 14/47 (2005.12); C12N 15/00 (2005.12); C12N 15/09 (2005.12); C12N 15/10 (2005.12); C12N 15/11 (2005.12); C12N 15/13 (2005.12); C12Q 1/02 (2005.12); G01N 33/50 (2005.12); A01K 67/0275 (2023.12); A61K 31/7088 (2005.12); A61K 31/7105 (2005.12); A61K 31/711 (2005.12); A61K 31/7115 (2005.12); A61K 31/7125 (2005.12); A61K 35/12 (2014.12); A61P 3/00 (2005.12); C12N 15/85 (2005.12); C12Q 1/6883 (2017.12);
U.S. Cl.
CPC ...
C07K 14/47 (2012.12); A61K 9/0019 (2012.12); A61K 38/17 (2012.12); C12Q 1/025 (2012.12); G01N 33/5058 (2012.12); A01K 67/0275 (2012.12); A01K 2207/05 (2012.12); A01K 2207/10 (2012.12); A01K 2207/20 (2012.12); A01K 2217/206 (2012.12); A01K 2267/03 (2012.12); A01K 2267/0306 (2012.12); A01K 2267/0318 (2012.12); A01K 2267/0393 (2012.12); A61K 31/7088 (2012.12); A61K 31/7105 (2012.12); A61K 31/711 (2012.12); A61K 31/7115 (2012.12); A61K 31/7125 (2012.12); A61K 35/12 (2012.12); A61K 38/00 (2012.12); A61K 38/1709 (2012.12); A61K 48/00 (2012.12); A61K 48/005 (2012.12); A61K 48/0066 (2012.12); A61K 2300/00 (2012.12); A61P 3/00 (2017.12); C12N 15/85 (2012.12); C12Q 1/6883 (2012.12); C12Q 2600/106 (2012.12); G01N 33/5023 (2012.12); G01N 2333/47 (2012.12); G01N 2500/10 (2012.12); G01N 2800/56 (2012.12);
Abstract
Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.