The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Mar. 31, 2020
Meryx, Inc., Chapel Hill, NC (US);
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Betta Pharmaceuticals Co., Ltd, Zhejiang, CN;
Xiaodong Wang, Chapel Hill, NC (US);
Weihe Zhang, Vestavia, AL (US);
Xiangyong Liu, Zhejiang, CN;
Changlong Han, Zhejiang, CN;
Zongquan Li, Zhejiang, CN;
Meryx, Inc., Chapel Hill, NC (US);
Abstract
The invention relates to new crystal forms of compound (trans)-4-((2-cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl) cyclohexanol trihydrochloride, its hydrate, or solvate, as shown in Formula I. The invention also relates to methods for preparation of the described compound, crystal form, and related intermediate compounds, as well as pharmaceutical compositions containing the compounds. Further described is, the use of the compounds or crystal forms in the production of a medicament for the treatment of a disease, symptom, or condition, or the use in treatment of a disease, symptom or condition.