The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Mar. 07, 2019
Applicant:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Inventors:
Alexandra Rose Lucas, Tempe, AZ (US);
Alfred S. Lewin, Gainesville, FL (US);
Cristhian J. Ildefonso, Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2005.12); A61P 27/02 (2005.12); A61P 29/00 (2005.12); A61P 37/06 (2005.12); C07K 14/81 (2005.12); C12N 15/86 (2005.12);
U.S. Cl.
CPC ...
A61K 48/005 (2012.12); A61K 48/0075 (2012.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 37/06 (2017.12); C07K 14/81 (2012.12); C12N 15/86 (2012.12); C12N 2750/14123 (2012.12); C12N 2750/14143 (2012.12);
Abstract
In some aspects, the disclosure relates to compositions and methods that are useful for treating inflammatory disorders and conditions. In some embodiments, the disclosure provides recombinant adeno-associated virus (rAAV) vectors and particles encoding a transgene that expresses a Myxomavirus serine proteinase inhibitor (Serp) protein (e.g., Serp-1) and methods for treating inflammatory disorders using the same.