The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Oct. 31, 2022
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Jian Jin, New York, NY (US);
Ramon Parsons, Manhasset, NY (US);
Ilias Stratikopoulos, New York, NY (US);
Xiaobao Yang, New York, NY (US);
Anqi Ma, New York, NY (US);
Assignee:
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2005.12); A61K 31/437 (2005.12); A61K 31/444 (2005.12); A61K 31/496 (2005.12); A61P 35/00 (2005.12); A61P 35/02 (2005.12); A61P 43/00 (2005.12); C07D 405/12 (2005.12); C07D 405/14 (2005.12); C07D 417/14 (2005.12); C07D 471/04 (2005.12);
U.S. Cl.
CPC ...
A61K 31/496 (2012.12); A61K 31/444 (2012.12); C07D 401/14 (2012.12); C07D 405/12 (2012.12); C07D 405/14 (2012.12); C07D 417/14 (2012.12);
Abstract
Methods for designing bivalent compounds which selectively degrade/disrupt EZH2 and compositions and methods of using such degraders/disruptors to treat EZH2-mediated cancer are provided.