The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2025

Filed:

Nov. 04, 2019
Applicant:

Shifa Biomedical Corporation, Malvern, PA (US);

Inventors:

Shaker A. Mousa, Wynantskill, NY (US);

Nabil A. Elshourbagy, West Chester, PA (US);

Harold V. Meyers, Weston, MA (US);

Sherin Salaheldin Abdel-Meguid, Exton, PA (US);

Assignee:

SHIFA BIOMEDICAL CORPORATION, Malvern, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2005.12); A61K 9/51 (2005.12); A61K 45/06 (2005.12); A61K 47/55 (2016.12);
U.S. Cl.
CPC ...
A61K 31/422 (2012.12); A61K 9/5138 (2012.12); A61K 9/5153 (2012.12); A61K 9/5161 (2012.12); A61K 45/06 (2012.12); A61K 47/55 (2017.07);
Abstract

Disclosed are Nanoformulated compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL- and related cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.


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