The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Jun. 01, 2018
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
Applicant:
Biontech SE, Mainz, DE;
Inventor:
Ugur Sahin, Mainz, DE;
Assignee:
BioNTech SE, Mainz, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); A61K 39/0011 (2013.01); A61K 39/001156 (2018.08); A61K 39/001188 (2018.08); A61K 2039/53 (2013.01); A61K 2039/876 (2018.08); G01N 2333/70514 (2013.01); G01N 2333/70517 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention relates to methods for predicting whether peptides or polypeptides comprising disease specific amino acid modifications, in particular tumor-associated neo-antigens, comprise epitopes, in particular tumor-associated neo-epitopes, which are useful for immunotherapy such as for vaccination. The methods of the invention may be used, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.