The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Aug. 25, 2020
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Frank Bergmann, Iffeldorf, DE;
Peter J. Crisalli, Mountain View, CA (US);
Sara Kelley, Pleasant Hill, CA (US);
Omid Khakshoor, Lathrop, CA (US);
Hannes Kuchelmeister, Munich, DE;
Meng Taing, Hayward, CA (US);
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Abstract
The disclosure relates to tagged nucleoside compounds comprising a nucleotide polyphosphate covalently attached to a tag, wherein the compound is a polymerase substrate and the polymer moiety is capable of entering a nanopore linked to the polymerase and thereby altering the flow of ions through the nanopore. The disclosure also provides methods for preparing the tagged nucleoside compounds and for their use as tags in nanopore-based nucleic acid detection and sequencing.