The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Oct. 18, 2019
Ohio State Innovation Foundation, Columbus, OH (US);
Daniel Gallego-Perez, Columbus, OH (US);
William Carson, Hilliard, OH (US);
Silvia M. Duarte Sanmiguel, Columbus, OH (US);
Natalia Higuita-Castro, Columbus, OH (US);
Ohio State Innovation Foundation, Columbus, OH (US);
Abstract
Disclosed herein is a method of 'reprogramming' highly motile cells found in tumors, such as these highly motile GSC and/or MDSC clones, into “auto-destructive” cell “missiles” (referred to herein as therapeutic stealth cells) that can seek and destroy new foci of recurrence within the body, such as the brain. Cells with enhanced motility can be sorted out from heterogeneous populations and then be rendered “auto-destructive” by deterministic delivery of an anti-cancer agent, such as an oncolytic virus plasmid cocktail.