The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2025

Filed:

Feb. 12, 2019
Applicant:

Maco Pharma, Mouvaux, FR;

Inventors:

Bruno Delorme, Marcq-en-Baroeul, FR;

Sabrina Viau, Wasquehal, FR;

Assignee:

Maco Pharma, Mouvaux, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 41/17 (2020.01); C12N 5/078 (2010.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0018 (2013.01); A61K 41/17 (2020.01); C12N 5/0644 (2013.01); C12N 9/6437 (2013.01); C12N 9/644 (2013.01); C12N 9/6443 (2013.01); C12N 2529/10 (2013.01);
Abstract

The invention relates to a method for preparing an irradiated platelet lysate, comprising the steps of providing a starting platelet lysate having platelet factors including growth factors and plasma proteins including coagulation factors and proteins other than the coagulation factors. Double irradiation of the starting platelet lysate, using UVC radiation and ionizing radiation. The double irradiation with UVC radiation and ionizing radiation being arranged to retain at least 75% of the total protein concentration of the starting platelet lysate, while reducing, by at least 40%, the concentration of at least one of the coagulation factors including fibrinogen, factor II, factor VII, factor IX, factor X and factor XI of the starting platelet lysate.


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