The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Mar. 24, 2023
Celyntra Therapeutics SA, Mont-Saint-Guibert, BE;
Danmarks Tekniske Universitet, KGS Lyngby, DK;
Ryan T. Gill, Denver, CO (US);
Tanya Warnecke, Boulder, CO (US);
Andrea Barghetti, Copenhagen, DK;
Line Dahl Poulsen, Ballerup, DK;
Celyntra Therapeutics SA, Mont-Saint-Guibert, BE;
DANMARKS TEKNISKE UNIVERSITET, KGS Lyngby, DK;
Abstract
The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR-Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of targeting, editing, and/or modifying a nucleic acid using the engineered CRISPR system, and compositions and cells comprising the engineered CRISPR system.