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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12270044 B1

PDFFull Text
Date of Patent:
Apr. 08, 2025

Filed:

Mar. 24, 2023

Crispr systems with engineered dual guide nucleic acids

Applicants:

Celyntra Therapeutics SA, Mont-Saint-Guibert, BE;

Danmarks Tekniske Universitet, KGS Lyngby, DK;

Inventors:

Ryan T. Gill, Denver, CO (US);

Tanya Warnecke, Boulder, CO (US);

Andrea Barghetti, Copenhagen, DK;

Line Dahl Poulsen, Ballerup, DK;

Assignees:

Celyntra Therapeutics SA, Mont-Saint-Guibert, BE;

DANMARKS TEKNISKE UNIVERSITET, KGS Lyngby, DK;

Attorney:

N.V. Nederlandsch Octrooibureau

Primary Examiner:

Neil P Hammell

Assistant Examiner:

Khaleda B Hasan

Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/70 (2006.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/70 (2013.01); C12N 15/85 (2013.01); C12N 2310/20 (2017.05); C12N 2800/22 (2013.01);
Abstract

The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR-Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of targeting, editing, and/or modifying a nucleic acid using the engineered CRISPR system, and compositions and cells comprising the engineered CRISPR system.

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Quick Actions:

Gill, Ryan. (2025). Crispr systems with engineered dual guide nucleic acids (U.S. Patent No. 12270044). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12270044

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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