The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Nov. 26, 2019
Nanjing Genscript Biotech Co., Ltd., Nanjing, CN;
Liusong Yin, Nanjing, CN;
Tielin Zhou, Singapore, SG;
Xinpo Jiang, Vancouver, CA;
Zhuo Fang, Nanjing, CN;
Yanling Mi, Nanjing, CN;
Chunchen Wu, Nanjing, CN;
NANJING GENSCRIPT BIOTECH CO., LTD., Jiangsu, CN;
Abstract
The present invention relates to a humanized anti-human OX40 monoclonal antibody, and a preparation method and use thereof. The humanized anti-human OX40 monoclonal antibody provided in the present invention has high affinity and specificity for OX40, and can stimulate T cells to secrete cytokines, for example, specifically activate the positive immune regulation by OX40 and activate T cells to secrete cytokines. Therefore, the functional humanized anti-human OX40 monoclonal antibody provided in the present invention activates T cells by activating the OX40 signaling pathway, thereby achieving the purpose of tumor immunotherapy.