The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Aug. 21, 2023
Applicant:
Ptc Therapeutics Mp, Inc., South Plainfield, NJ (US);
Inventor:
Daniel E. Levy, San Mateo, CA (US);
Assignee:
PTC Therapeutics MP, Inc., Warren, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 475/04 (2006.01); A61K 31/495 (2006.01); A61P 3/00 (2006.01); A61P 5/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 475/04 (2013.01);
Abstract
Disclosed are crystalline forms of sepiapterin free base selected from polymorphs A, B, C, D, E, F, and G, and combinations thereof, as well as crystalline polymorphs of salts of sepiapterin. Also disclosed are pharmaceutical compositions containing one or more such polymorphs and methods for preparing such polymorphs. Sepiapterin is useful in the treatment of a number diseases associated with low cellular levels of BH4, for example, phenylketonuria.