The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Jun. 07, 2021
Applicant:
University of Kansas, Lawrence, KS (US);
Inventors:
Brian S. J. Blagg, Niles, MI (US);
Vincent Matthew Crowley, Lawrence, KS (US);
Assignee:
University of Kansas, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/94 (2006.01); A61K 31/216 (2006.01); A61K 31/44 (2006.01); A61P 27/02 (2006.01); A61P 35/04 (2006.01); C07C 69/76 (2006.01); C07C 69/78 (2006.01); C07C 69/88 (2006.01); C07C 219/34 (2006.01); C07C 229/52 (2006.01); C07D 213/55 (2006.01); C07D 213/643 (2006.01);
U.S. Cl.
CPC ...
C07C 69/94 (2013.01); A61K 31/216 (2013.01); A61K 31/44 (2013.01); A61P 27/02 (2018.01); A61P 35/04 (2018.01); C07C 69/76 (2013.01); C07C 69/78 (2013.01); C07C 219/34 (2013.01); C07C 229/52 (2013.01); C07D 213/55 (2013.01); C07D 213/643 (2013.01);
Abstract
The present technology provides compounds selective for the Grp94 isoform, as well as compositions including such compounds, that are useful for treatment of multiple myeloma, melanoma, lung cancer, hepatocellular carcinoma, breast cancer, prostate cancer, and/or glaucoma. Methods using the compound are also provided.