The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2025

Filed:

Sep. 13, 2019
Applicant:

Luca Science Inc., Chuo-ku, JP;

Inventors:

Masashi Suganuma, Aichi, JP;

Hideyoshi Harashima, Hokkaido, JP;

Yuma Yamada, Hokkaido, JP;

Daisuke Sasaki, Hokkaido, JP;

Takafumi Yokota, Osaka, JP;

Assignee:

LUCA Science Inc., Chuo-ku, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 35/17 (2015.01); A61K 35/34 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 35/17 (2013.01); A61K 35/34 (2013.01);
Abstract

Provided herein are a method for isolation and transplantation of intact mitochondria to a lymphoid organ (a primary lymphoid tissue or a secondary lymphoid tissue), a composition of cells prepared by using a method described herein, and a method for manufacturing cells described herein. In particular, provided herein are methods of isolating intact mitochondria from a donor cell. Also provided herein are methods of transplanting mitochondria into a recipient cell. In some aspects, the methods can be performed in vivo. Further provided are a composition of cells that include the cells prepared using the methods of the present invention.


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