The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2025
Filed:
Apr. 25, 2022
Applicant:
Aurigene Oncology Limited, Karnataka, IN;
Inventors:
Muralidhara Ramachandra, Bangalore, IN;
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Girish Chandrappa Daginakatte, Bangalore, IN;
Kiran Aithal Balkudru, Bangalore, IN;
Assignee:
AURIGENE ONCOLOGY LIMITED, Karnataka, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); A61P 35/00 (2018.01); A61K 45/06 (2013.01); C07K 16/2887 (2013.01);
Abstract
The present invention relates to a composition of a CD47-SIRPα blocking agent and one or more anti-cancer agent(s), where the CD47-SIRPα blocking agents are represented by a compound of formula (I). The present invention also relates to a method of treating a cancer in a subject by administering a therapeutically effective amount of a CD47-SIRPα blocking agent represented by formula (I) in combination with one or more anti-cancer agent(s).