The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2025

Filed:

Dec. 17, 2019
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Christine Ellen Bulawa, Arlington, MA (US);

James Allan Fleming, Arlington, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/423 (2006.01); A61K 31/4025 (2006.01); A61K 31/4245 (2006.01); A61P 25/00 (2006.01); C07K 16/18 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/423 (2013.01); A61K 31/4025 (2013.01); A61K 31/4245 (2013.01); A61P 25/00 (2018.01); C07K 16/18 (2013.01); C12N 15/113 (2013.01);
Abstract

The present invention relates to pharmaceutical compositions and methods of treatment comprising administering to a patient in need thereof a combination of a benzoxazole derivative transthyretin stabilizer or a pharmaceutically acceptable salt or prodrug thereof and an additional therapeutic agent for the treatment of transthyretin amyloidosis. Particularly, the present invention relates to pharmaceutical compositions and methods of treatment comprising administering to a patient in need thereof 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid or a pharmaceutically acceptable salt or prodrug thereof and one or more additional therapeutic agent for the treatment of transthyretin amyloidosis.


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