The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Jul. 02, 2019
Methods of treating refractory inflammatory disease using transcriptomic and genetic risk signatures
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Alka Potdar, Cumming, GA (US);
Dermot P. McGovern, Los Angeles, CA (US);
Janine Bilsborough, Simi Valley, CA (US);
Stephan Targan, Santa Monica, CA (US);
Assignee:
CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Disclosed herein are methods, kits and compositions for treating an inflammatory disease. These methods. kits and compositions may be particularly useful for subjects carrying a risk genotype and/or expressing a transcriptomic risk signature that is indicative of severe inflammatory disease phenotypes for which existing treatment options are limited.