The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Nov. 26, 2019
Applicant:

Oxford Nanopore Technologies Plc, Oxford, GB;

Inventor:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); G06F 18/214 (2023.01); G06N 3/045 (2023.01); G06N 3/084 (2023.01); G06N 20/20 (2019.01); G16B 30/00 (2019.01); G16B 40/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); G06F 18/214 (2023.01); G06N 3/045 (2023.01); G06N 3/084 (2013.01); G06N 20/20 (2019.01); G16B 30/00 (2019.02); G16B 40/10 (2019.02);
Abstract

Techniques for estimating a polymer sequence of a polymer based on a signal produced as a result of translocation of the polymer through a nanopore are described. The techniques may analyze portions of the signal to estimate whether there was a transition in the polymer sequence during each respective portion and which units of the sequence the transition was between. The techniques may comprise operation of one or more neural networks into which data from the signal may be input. The techniques may include generating a plurality of weights for a portion of the signal, wherein each weight is associated with a transition between labeled units of the polymer. The weights may be indicative of a likelihood that a transition occurred between a first of the labeled units to a second of the labeled units within the portion of the signal.


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