The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Apr. 14, 2017
Applicant:
Genomatica, Inc., San Diego, CA (US);
Inventors:
Anthony P. Burgard, Bellefonte, PA (US);
Robin E. Osterhout, San Diego, CA (US);
Stephen J. Van Dien, Encinitas, CA (US);
Cara Ann Tracewell, Solana Beach, CA (US);
Priti Pharkya, San Diego, CA (US);
Stefan Andrae, San Diego, CA (US);
Assignee:
Genomatica, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/18 (2006.01); C07D 207/12 (2006.01); C08G 18/32 (2006.01); C08G 63/06 (2006.01); C08G 63/12 (2006.01); C08G 63/66 (2006.01); C08G 69/26 (2006.01); C12N 9/04 (2006.01); C12N 9/06 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12P 7/24 (2006.01); C12P 19/02 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C07D 207/12 (2013.01); C08G 18/3206 (2013.01); C08G 63/06 (2013.01); C08G 63/12 (2013.01); C08G 63/66 (2013.01); C08G 69/26 (2013.01); C12N 9/0006 (2013.01); C12N 9/0028 (2013.01); C12N 9/1007 (2013.01); C12N 9/88 (2013.01); C12P 7/24 (2013.01); C12P 19/02 (2013.01); C12Y 101/01244 (2013.01); C12Y 101/02007 (2013.01); C12Y 105/0102 (2013.01); C12Y 201/01 (2013.01); C12Y 101/01224 (2013.01); C12Y 201/0109 (2013.01); C12Y 402/01 (2013.01); Y02P 20/52 (2015.11);
Abstract
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 1,4-butanediol (BDO). Also provided herein are methods for using such an organism to produce BDO.