The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Jul. 02, 2021
Applicants:
Research Foundation of the City University of New York, New York, NY (US);
Japanese Foundation for Cancer Research, Tokyo, JP;
Inventors:
Assignees:
Research Foundation of the City University of New York, New York, NY (US);
Japanese Foundation for Cancer Research, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C12N 5/0006 (2013.01);
Abstract
A method for enhancing extracellular vesicle production is described. A peptide that induces polymer formation is incubated with a cell culture which results in enhanced EV production. The peptide penetrates the cells and subsequently polymerizes upon exposure to enzymes (e.g. phosphatase) within the cell. The cells that contain the newly formed polymers have an increased production of EVs. These EVs can be harvested using centrifugation techniques.