The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Jul. 19, 2022
Applicants:

Sidney Hecht, Phoenix, AZ (US);

Larisa (Liza) Dedkova, Scottsdale, AZ (US);

Rumit Maini, Tempe, AZ (US);

Sandipan Roy Chowdhury, Tempe, AZ (US);

Rakesh Paul, Baltimore, MD (US);

Inventors:

Sidney Hecht, Phoenix, AZ (US);

Larisa (Liza) Dedkova, Scottsdale, AZ (US);

Rumit Maini, Tempe, AZ (US);

Sandipan Roy Chowdhury, Tempe, AZ (US);

Rakesh Paul, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/67 (2006.01); C07D 263/34 (2006.01); C07D 277/593 (2006.01); C12N 9/06 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/67 (2013.01); C07D 263/34 (2013.01); C07D 277/593 (2013.01); C12N 9/003 (2013.01); C12N 15/11 (2013.01); C12Y 105/01003 (2013.01);
Abstract

Modified ribosomes that were selected using a dipeptidyl-puromycin aminonucleoside are used to mediate site-specific incorporation of one or more peptides and peptidomimetics into protein in a cell free translation system. In addition, new fluorescent dipeptidomimetics have been synthesized and incorporated into proteins, as well as modified proteins containing one or more non-naturally occurring dipeptides.


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