The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Sep. 02, 2021
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

William W. Metcalf, Savoy, IL (US);

Alexander L. Polidore, Urbana, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/662 (2006.01); A01N 57/20 (2006.01); C07F 9/38 (2006.01);
U.S. Cl.
CPC ...
C07F 9/3826 (2013.01); A01N 57/20 (2013.01);
Abstract

Here we show thatproduces at least three phosphonates, two of which were purified and structurally characterized. The first, designated pantaphos, was shown to be 2-(hydroxy(phosphono)methyl)maleate; the second, a probable biosynthetic precursor, was shown to be 2-(phosphonomethyl)maleate. Purified pantaphos is both necessary and sufficient for the hallmark lesions of onion center rot. Moreover, when tested against mustard seedlings, the phytotoxic activity of pantaphos was comparable to the widely used herbicides glyphosate and phosphinothricin. Pantaphos was also active against a variety of human cell lines.


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