The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
May. 16, 2022
Applicant:
Kallyope, Inc., New York, NY (US);
Inventors:
Iyassu Sebhat, Jersey City, NJ (US);
Shuwen He, Fanwood, NJ (US);
Assignee:
KALLYOPE, INC., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/38 (2006.01); A61K 31/10 (2006.01); A61K 31/662 (2006.01); A61K 31/675 (2006.01); C07C 309/24 (2006.01); C07F 9/30 (2006.01); C07F 9/58 (2006.01); C07F 9/59 (2006.01);
U.S. Cl.
CPC ...
C07F 9/3808 (2013.01); A61K 31/10 (2013.01); A61K 31/662 (2013.01); A61K 31/675 (2013.01); C07C 309/24 (2013.01); C07F 9/301 (2013.01); C07F 9/58 (2013.01); C07F 9/59 (2013.01);
Abstract
This disclosure is directed, at least in part, to GPR40 agonists useful for the treatment of conditions or disorders involving the gut-brain axis. In some embodiments, the GPR40 agonists are gut-restricted compounds. In some embodiments, the GPR40 agonists are full agonists or partial agonists. In some embodiments, the condition or disorder is a metabolic disorder, such as diabetes, obesity, nonalcoholic steatohepatitis (NASH), or a nutritional disorder such as short bowel syndrome.