The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Jul. 11, 2023
Applicant:

Tetra Discovery Partners, Llc, Grand Rapids, MI (US);

Inventors:

Mark E. Gurney, Grand Rapids, MI (US);

Timothy J. Hagen, Lisle, IL (US);

Xuesheng Mo, Naperville, IL (US);

A. Samuel Vellekoop, Altamont, NY (US);

Donna L. Romero, Chesterfield, MO (US);

Robert Campbell, Niskayuna, NY (US);

Joel R. Walker, Schenectady, NY (US);

Lei Zhu, Schenectady, NY (US);

Assignee:

Tetra Discovery Partners, Grand Rapids, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/72 (2006.01); A61K 31/435 (2006.01); A61K 31/44 (2006.01); A61K 31/4418 (2006.01); A61K 31/496 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); C07D 213/56 (2006.01); C07D 213/74 (2006.01); C07D 221/04 (2006.01); C07D 239/26 (2006.01); C07D 239/70 (2006.01); C07D 251/22 (2006.01); C07D 251/30 (2006.01); C07D 251/42 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 495/04 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07F 5/027 (2013.01); A61K 31/435 (2013.01); A61K 31/44 (2013.01); A61K 31/4418 (2013.01); A61K 31/496 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/69 (2013.01); A61K 45/06 (2013.01); C07D 213/56 (2013.01); C07D 213/72 (2013.01); C07D 213/74 (2013.01); C07D 221/04 (2013.01); C07D 239/26 (2013.01); C07D 239/70 (2013.01); C07D 251/22 (2013.01); C07D 251/30 (2013.01); C07D 251/42 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 495/04 (2013.01); C07F 5/025 (2013.01);
Abstract

The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.


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