The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
May. 06, 2019
Beijing Increase Innovative Drug Co., Ltd., Beijing, CN;
Baoxian Zhang, Beijing, CN;
Hongwu Zhang, Beijing, CN;
Jie Hu, Beijing, CN;
Zhiyun Kang, Beijing, CN;
Chunmei Xue, Beijing, CN;
Wenhui Li, Beijing, CN;
Yanwei Song, Beijing, CN;
Zhenzhen Wu, Beijing, CN;
Anping Chen, Beijing, CN;
Fang Wang, Beijing, CN;
Hengchun Ren, Beijing, CN;
Jun Li, Beijing, CN;
Beijing Increase Innovative Drug Co., LTD, Beijing, CN;
Abstract
Provided are a Rho kinase inhibitor, a method for preparing same and the uses thereof. The Rho kinase inhibitor designates a compound of Formula I, a stereoisomer thereof or pharmaceutically acceptable salt thereof. The Rho kinase inhibitor promotes endothelial cells and endothelin expression, prostenin expression, and vascular factors NO synthesis and secretion, has a promoting effect on proprostin expression independently of the doses used, shows lower toxicity, while being safer.