The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Aug. 02, 2023
Qingdao University of Science and Technology, Qingdao, CN;
Peizhe Cui, Qingdao, CN;
Jianguang Qi, Qingdao, CN;
Wenhui Xu, Qingdao, CN;
Yinglong Wang, Qingdao, CN;
Zhaoyou Zhu, Qingdao, CN;
Kaiguang Wang, Qingdao, CN;
Xin Li, Qingdao, CN;
Fanqing Meng, Qingdao, CN;
Limei Zhong, Qingdao, CN;
Shuli Yin, Qingdao, CN;
Lei Han, Qingdao, CN;
Jianbo Jia, Qingdao, CN;
Zhonghui Zheng, Qingdao, CN;
Qingdao University of Science and Technology, Qingdao, CN;
Abstract
A process and a device for continuous flow side-chain alkylation which relate to the technical field of organic synthesis. In this process and the device for continuous flow side-chain alkylation, an ibuprofen raw material is prepared with alkylbenzene as a raw material. This raw material alkylbenzene is easily available and has a low cost, and is suitable for scale-up production. Moreover, an entire preparation process adopts continuous chemical synthesis, and a reaction time of each stage can be precisely controlled, which is beneficial to control a total reaction time and reduce an amount of impurities produced. In this way, a purity and a yield of the ibuprofen raw material are improved. In summary, a continuous synthesis method for side-chain alkylation of alkylbenzene provided by the present disclosure shows a low cost and a high yield.