The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Jul. 28, 2023
Applicant:
Bio-rad Laboratories, Inc., Hercules, CA (US);
Inventors:
Christopher Belisle, Walnut Creek, CA (US);
Jiali Liao, San Ramon, CA (US);
Edwin Lozano, Berkeley, CA (US);
Assignee:
BIO-RAD LABORATORIES, INC., Hercules, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 20/28 (2006.01); B01D 15/38 (2006.01); B01J 20/285 (2006.01); B01J 20/289 (2006.01); B01J 20/30 (2006.01); C07K 1/16 (2006.01);
U.S. Cl.
CPC ...
B01J 20/285 (2013.01); B01D 15/3809 (2013.01); B01D 15/3847 (2013.01); B01J 20/28085 (2013.01); B01J 20/289 (2013.01); B01J 20/3042 (2013.01); C07K 1/165 (2013.01); B01J 2220/52 (2013.01);
Abstract
The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix.