The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Nov. 26, 2019
Applicants:
Crispr Therapeutics Ag, Zug, CH;
Bayer Healthcare Llc, Whippany, NJ (US);
Inventors:
Christopher J. Cheng, San Francisco, CA (US);
Andrew Scharenberg, San Francisco, CA (US);
Kui Wang, San Francisco, CA (US);
Shailendra Sane, San Francisco, CA (US);
Assignees:
CRISPR THERAPEUTICS AG, Zug, CH;
BAYER HEALTHCARE LLC, Whippany, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0025 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12N 15/88 (2013.01); C12N 2310/20 (2017.05); C12N 2320/32 (2013.01);
Abstract
The present disclosure relates generally to novel lipid nanoparticle (LNP)-based compositions useful for, e.g., the delivery of a site-specific endonuclease or a nucleic acid molecule encoding same, into a target cell. Some embodiments of the disclosure relate to compositions and methods for editing the genome of a cell, which involve contacting the cell with an LNP composition as described herein.