The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Jul. 05, 2023
Applicant:
Neomics Pharmaceuticals Llc, Gaithersburg, MD (US);
Inventors:
William A. Comrie, Silver Spring, MD (US);
Wenshan Hao, Parsippany, NJ (US);
Assignee:
Neomics Pharmaceuticals LLC, Rockville, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
A61K 39/464417 (2023.05); A61K 39/4611 (2023.05); A61K 39/4631 (2023.05); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/2878 (2013.01); C12N 15/62 (2013.01); A61K 2239/13 (2023.05); A61K 2239/22 (2023.05); A61K 2239/48 (2023.05); C07K 2317/569 (2013.01); C07K 2319/33 (2013.01);
Abstract
The present application relates to functionally improved third generation BCMA-CARs comprising modified intracellular co-stimulatory domains, which can be used in adoptive cell therapy, e.g., in treatment of diseases and disorders such as cancer.