The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Feb. 06, 2020
Universidad Central Del Caribe, Bayamón, PR;
St. Jude Children's Research Hospital, Inc., Memphis, TN (US);
Michelle M. Martinez-Montemayor, San Juan, PR;
Fatima Rivas, Germantown, TN (US);
UNIVERSIDAD CENTRAL DEL CARIBE, Bayamón, PR;
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., Memphis, TN (US);
Abstract
The bioactive compounds ofextract (GLE) responsible for anticancer activity were elucidated using NMR, X-ray crystallography and analogue derivatization, as well as anti-cancer activity studies. Structures of the seven most abundant GLE compounds are disclosed. Their selective efficacy against triple negative (TNBC) and inflammatory breast cancers (IBC) and other human cancer cell types (solid and blood malignancies) was shown, confirming potential their as anticancer agents.