The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Jan. 12, 2024
Applicant:
Sumitomo Pharma Co., Ltd., Osaka, JP;
Inventors:
Seiji Kamioka, Osaka, JP;
Hitoshi Ban, Osaka, JP;
Naoaki Shimada, Osaka, JP;
Wataru Hirose, Osaka, JP;
Akihiko Arakawa, Odawara, JP;
Kazuto Yamazaki, Ikoma, JP;
Kenjiro Hira, Osaka, JP;
Assignee:
Sumitomo Pharma Co., Ltd., Osaka, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract
The compound of formula (1a) wherein p is 1 or 2, R-Rare hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.