The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Jul. 11, 2023
Applicants:

The Scripps Research Institute, La Jolla, CA (US);

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Luke L. Lairson, San Diego, CA (US);

Michael J. Bollong, San Diego, CA (US);

Peter G. Schultz, La Jolla, CA (US);

Sendurai A. Mani, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/502 (2006.01); A61K 31/437 (2006.01); A61K 31/4704 (2006.01); A61K 31/4741 (2006.01); A61K 31/497 (2006.01); A61K 31/4985 (2006.01); A61K 31/551 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/502 (2013.01); A61K 31/437 (2013.01); A61K 31/4704 (2013.01); A61K 31/4741 (2013.01); A61K 31/497 (2013.01); A61K 31/4985 (2013.01); A61K 31/551 (2013.01); A61P 35/00 (2018.01);
Abstract

The present disclosure provides compounds, their pharmaceutical compositions, and methods of their use for treating mesenchymally-derived or mesenchymally-transformed cancers, such as breast cancers and sarcomas, and for treating diseases or disorders that are characterized by the expression of vimentin.


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