The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Aug. 16, 2023
Acerta Pharma B.v., Oss, NL;
Ahmed Hamdy, Santa Cruz, CA (US);
Wayne Rothbaum, New York, NY (US);
Raquel Izumi, San Carlos, CA (US);
Brian Lannutti, Solana Beach, CA (US);
Todd Covey, San Carlos, CA (US);
Roger Ulrich, Sammamish, WA (US);
Dave Johnson, Aptos, CA (US);
Tjeerd Barf, Ravenstein, NL;
Allard Kaptein, Zaltbommel, NL;
Acerta Pharma B.V., Oss, NL;
Abstract
Therapeutic methods of treating chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL) are described. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating subtypes of CLL and SLL using a BTK inhibitor, including subtypes of CLL in patients sensitive to thrombosis and subtypes of CLL that increase monocytes and NK cells in peripheral blood after treatment with a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a combination of a BTK inhibitor and an anti-CD20 antibody.