The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2025
Filed:
Nov. 18, 2022
Kronos Bio, Inc., San Mateo, CA (US);
Peter A. Blomgren, Issaquah, WA (US);
Kevin S. Currie, North Bend, WA (US);
Jeffrey E. Kropf, Issaquah, WA (US);
Seung H. Lee, Sammamish, WA (US);
Jennifer R. Lo, Seattle, WA (US);
Scott A. Mitchell, Kenmore, WA (US);
Aaron C. Schmitt, Hamden, CT (US);
Jin-Ming Xiong, Bel Air, MD (US);
Jianjun Xu, Bellevue, WA (US);
Sundaramoorthi Swaminathan, Burlingame, CA (US);
Zhongdong Zhao, Bellevue, WA (US);
Kronos Bio, Inc., San Mateo, CA (US);
Abstract
The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, a Syk inhibitor is a crystalline monomesylate salt of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo-[1,2-a]pyrazin-8-amine of formula 2: