The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2025

Filed:

Mar. 25, 2024
Applicant:

Remedi, Inc., Norwell, MA (US);

Inventors:

Tom Spector, Chapel Hill, NC (US);

Jeremy Ford, Norwell, MA (US);

Thomas A. Krenitsky, Chapel Hill, NC (US);

Assignee:

Remedi, Inc., Norwell, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/39 (2006.01); A61K 31/4045 (2006.01); A61P 25/24 (2006.01);
U.S. Cl.
CPC ...
A61K 31/39 (2013.01); A61K 31/4045 (2013.01); A61P 25/24 (2018.01);
Abstract

Disclosed are methods of treating a subject having a disease or disorder by administering a monoamine oxidase inhibitor in combination with a serotonin receptor agonist, which in some embodiments is a deuterated serotonin receptor agonist. In some aspects, the disclosure further relates to pharmaceutical compositions and kits comprising a monoamine oxidase inhibitor and a serotonin receptor agonist. In some embodiments, the monoamine oxidase inhibitor is a MAO-A-selective inhibitor such as CX157, and the serotonin receptor agonist is a serotonin 2A receptor agonist such as N,N-dimethyltryptamine (DMT), or deuterated DMT.


Find Patent Forward Citations

Loading…