The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2025

Filed:

Dec. 16, 2019
Applicants:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Charite Universitatsmedizin Berlin, Berlin, DE;

Inventors:

George L. Mutter, Boston, MA (US);

Peter Hufnagl, Berlin, DE;

Sebastian Lohmann, Berlin, DE;

David James Papke, Jr., Boston, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2022.01); G06T 7/00 (2017.01); G06V 10/426 (2022.01); G06V 20/69 (2022.01); A61B 90/20 (2016.01);
U.S. Cl.
CPC ...
G06V 10/426 (2022.01); G06T 7/0014 (2013.01); G06V 20/69 (2022.01); G06V 20/698 (2022.01); A61B 90/20 (2016.02); G06T 2207/10056 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/30024 (2013.01);
Abstract

Systems and methods are provided for augmenting digital analysis of lesions. An image of tissue having a glandular epithelial component is generated. The image represents a plurality of medium-scale epithelial components. For each of a plurality of cells within the image, a representative point is identified to provide a plurality of representative points for each of the plurality of medium-scale epithelial components. For each of a subset of the plurality of medium-scale epithelial components, a graph connecting the plurality of representative points is constructed. A plurality of classification features is extracted for each of the subset of medium-scale epithelial components from the graph constructed for the medium-scale epithelial component. A clinical parameter is assigned to each medium-scale epithelial component according to the extracted plurality of classification features.


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