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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12259379 B1

PDFFull Text
Date of Patent:
Mar. 25, 2025

Filed:

Jun. 29, 2018

Method for predicting effect of tumor immunotherapy using tumor cytotoxic activity of peripheral blood t cells as index

Applicant:

Osaka University, Suita, JP;

Inventors:

Kota Iwahori, Suita, JP;

Hisashi Wada, Suita, JP;

Assignee:

OSAKA UNIVERSITY, Suita, JP;

Attorney:

MH2 Technology Law Group, LLP

Primary Examiner:

Hong Sang

Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); G16B 50/30 (2019.01); G16H 50/30 (2018.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); C07K 16/30 (2013.01); G16B 50/30 (2019.02); G16H 50/30 (2018.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); G01N 2800/52 (2013.01);
Abstract

An object of the present invention is to provide a companion diagnostic for predicting the effect of a tumor immunotherapy. The effect of a tumor immunotherapy is predicted by a method including step 1: contacting directly or indirectly peripheral blood mononuclear cells collected from a patient who is a target for treatment of a malignant tumor with tumor cells in vitro; step 2: determining whether the tumor cells that contacted with the peripheral blood mononuclear cells in step 1 are damaged; and step 3: determining that the tumor immunotherapy is effective against the malignant tumor in the patient when the tumor cells are determined to have been damaged in step 2.

Find Patent Forward Citations

Iwahori, Kota. (2025). Method for predicting effect of tumor immunotherapy using tumor cytotoxic activity of peripheral blood t cells as index (U.S. Patent No. 12259379). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12259379

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