The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
May. 28, 2019
Applicant:
Praxis Precision Medicines, Inc., Boston, MA (US);
Inventor:
Steven Petrou, Eltham, AU;
Assignee:
Praxis Precision Medicines, Inc., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48728 (2013.01); G01N 2333/705 (2013.01);
Abstract
The present invention provides methods for determining the phenotype (e.g., gain-of-function or loss-of-function) of a mutation in an ion channel or receptor by using a dynamic voltage clamp. The invention also features methods of determining whether a mutation is a gain-of-function or loss-of-function mutation and treating a disease or disorder associated with the particular gain-of-function or loss-of-function mutation.