The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2025

Filed:

Nov. 22, 2021
Applicant:

Biodot, Inc., Irvine, CA (US);

Inventors:

Brian L. Kirk, Carlsbad, CA (US);

Anthony V. Lemmo, Mission Viejo, CA (US);

Thomas C. Tisone, Orange, CA (US);

Assignee:

Biodot, Inc., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/28 (2006.01); G01N 1/31 (2006.01); G01N 35/10 (2006.01);
U.S. Cl.
CPC ...
G01N 1/2813 (2013.01); G01N 1/312 (2013.01); B01J 2219/00378 (2013.01); B01J 2219/00527 (2013.01); B01J 2219/00743 (2013.01); G01N 2035/1023 (2013.01);
Abstract

Methods and techniques for controlled printing of a cell sample for karyotyping are provided. The methods can involve matrix printing using on-the-fly printing or dispensing to accurately spread cells within at least one cell sample on a surface in preparation for karyotyping, and further analysis. Advantageously, the methods result in a uniform distribution of chromosomes of the cell suspension or sample on the surface of a substrate which can be substantially discretely identified, and also provide for efficiency in a subsequent staining process and any further analysis of the stained chromosomes using a microscope or other imaging device.


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