The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Mar. 08, 2018
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
James R. Heath, Pasadena, CA (US);
Songming Peng, San Mateo, CA (US);
Alphonsus Hon-Chung Ng, Pasadena, CA (US);
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6804 (2018.01); B01L 3/00 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6804 (2013.01); B01L 3/502761 (2013.01); C12N 15/1037 (2013.01); C12N 15/1055 (2013.01); C12N 15/1065 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/02 (2013.01);
Abstract
Compositions and methods for identifying antigen-specific T cells, including determining paired T cell receptor sequences for a specific antigen, are described. Compositions and methods for identifying neoantigen-specific T cells are also described. Microfluidic devices useful for identifying antigen-specific T cells, and methods of using the same, are also described.