The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Nov. 05, 2020
Applicant:
Emendobio Inc., Wilmington, DE (US);
Inventors:
David Baram, Tel Aviv, IL;
Lior Izhar, Tel Aviv, IL;
Asael Herman, Ness-Ziona, IL;
Rafi Emmanuel, Ramla, IL;
Liat Rockah, Rishon LeZion, IL;
Nadav Marbach-Bar, Rehovot, IL;
Michal Golan Mashiach, Ness-Ziona, IL;
Joseph Georgeson, Rehovot, IL;
Assignee:
EmendoBio Inc., Wilmington, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 9/64 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6448 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12N 2310/20 (2017.05);
Abstract
Methods for inactivating in a cell a mutant allele of the elastase, neutrophil expressed gene (ELANE gene) gene having a mutation associated with severe congenital neutropenia (SCN) or cyclic neutropenia (CyN) wherein the mutant allele is selected from the group consisting of the ELANE mutants set forth in Table 1, the method comprising