The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Nov. 30, 2023
Applicants:
The University of Tokyo, Tokyo, JP;
Wisconsin Alumni Research Foundation (Warf), Madison, WI (US);
Inventors:
Assignees:
Wisconsin Alumni Research Foundation (WARF), Madison, WI (US);
The University of Tokyo, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 5/071 (2010.01); C12N 7/02 (2006.01); C12N 9/10 (2006.01); C12Q 1/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 5/0602 (2013.01); C12N 9/10 (2013.01); C12Q 1/04 (2013.01); C12Y 204/99001 (2013.01);
Abstract
A mammalian or avian cell line that expresses high levels of human influenza virus receptors is provided. In one embodiment, the cell line supports human influenza virus, e.g., human A/H3 influenza virus, isolation and growth much more effectively than corresponding conventional (unmodified) cells or in corresponding human virus receptor-overexpressing cells, and the propagated viruses may maintain higher genetic stability than in the corresponding cells.