The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2025

Filed:

Aug. 08, 2019
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Jongtae Yang, Eugene, OR (US);

Xin Wang, Eugene, OR (US);

Yi-Zhen Hu, Eugene, OR (US);

Kyle Gee, Springfield, OR (US);

Aimei Chen, Eugene, OR (US);

Aleksey Rukavishnikov, Eugene, OR (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09B 11/28 (2006.01); C07F 7/08 (2006.01); C07F 9/6561 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/6869 (2018.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C09B 11/28 (2013.01); C07F 7/0816 (2013.01); C07F 9/6561 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6869 (2013.01); G01N 33/582 (2013.01);
Abstract

Silicon-substituted rhodamine compounds are disclosed herein. Also described herein are SiR dyes comprising at least one vinyl group attached to the Si atom (10 position) of the SiR dye. Derivatives, functionalized versions, conjugates, kits, related synthetic methods and uses of SiR compounds also are provided. Silicon-rhodamine (SiR) dyes can provide bright fluorescence at far red wavelengths and exhibit good photostability. The compounds described herein can be useful for fluorescent labeling and detection of biological samples.


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