The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Apr. 06, 2020
Sichuan Kelun-biotech Biopharmaceutical Co., Ltd., Chengdu, CN;
Klus Pharma Inc., Cranbury, NJ (US);
Haijun Tian, Cranbury, NJ (US);
Dengnian Liu, Chengdu, CN;
Sujun Deng, Cranbury, NJ (US);
Marc Peter Ciucci, Cranbury, NJ (US);
Cheng Wang, Chengdu, CN;
Yong Zheng, Chengdu, CN;
Liang Xiao, Chengdu, CN;
Tongtong Xue, Chengdu, CN;
Jingyi Wang, Chengdu, CN;
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., Chengdu, CN;
Klus Pharma Inc., Cranbury, NJ (US);
Abstract
The present invention relates to the field of therapeutic monoclonal antibodies, and specifically provides an anti-FXI/FXIa antibody or an antigen-binding fragment thereof, nucleic acid molecules encoding same, and methods for preparing same. The anti-FXI/FXIa antibody or antigen-binding fragment thereof described in the present invention has specificity and high affinity to FXI/FXIa, and can effectively inhibit the activity of FXI/FXIa. Therefore, the present invention further provides a pharmaceutical composition comprising the antibody or antigen-binding fragment thereof, and a use thereof in the preparation of a drug which is used for the prevention and/or treatment of diseases or disorders related to coagulation or thromboembolism.