The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Mar. 27, 2024
Applicant:
Aarhus Universitet, Aarhus C, DK;
Inventors:
Nick Stub Laursen, Aarhus C, DK;
Dennis Vestergaard Pedersen, Aarhus C, DK;
Gregers Rom Andersen, Brabrand, DK;
Steffen Thiel, Risskov, DK;
Alessandra Zarantonello, Aarhus C, DK;
Rasmus Kjeldsen Jensen, Aarhus C, DK;
Henrik Pedersen, Aarhus C, DK;
Assignee:
Aarhus Universitet, Aarhus C, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/00 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 9/0019 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01);
Abstract
Single domain antibodies are provided, which are capable of specifically binding to an epitope of a human complement factor selected from the group consisting of C1q, C3, C4 and/or the proteolytic derivatives C3b and C4b. Further the use of the antibodies are provided for methods in modulating the activity of the complement system as well as methods of treating disorders associated with complement activation.