The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Dec. 06, 2019
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Hua Ying, Shanghai, CN;
Ling Zhang, Shanghai, CN;
Xiaoying Yang, Shanghai, CN;
Hu Ge, Shanghai, CN;
Weikang Tao, Shanghai, CN;
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;
Abstract
The present disclosure relates to a CD3 antibody and a pharmaceutical use thereof. Specifically, the present disclosure relates to forming a multi-specificity antibody by using CD3 antibody and binding molecules of another target. The multi-specificity antibody may simultaneously bind to CD3 and another tumor-associated antigen, and bind and activate CD3-positive T cells while binding tumor-associated antigen-expressing cells, thereby promoting T cells specifically killing tumor cells that express tumor-associated antigens. In addition, the present disclosure also provides a preparation and application of a multi-specific antibody.