The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Jul. 19, 2023
Guangdong Lewwin Pharmaceutical Research Institute Co., Ltd., Guangdong, CN;
Guangdong Cs-lewwin Drug Research Co., Ltd., Guangdong, CN;
Xingshu Li, Guangdong, CN;
Xinzi Chen, Guangdong, CN;
Wei Yang, Guangdong, CN;
Jianmin Guo, Guangdong, CN;
Guangdong Lewwin Pharmaceutical Research Institute Co., Ltd., Guangdong, CN;
Guangdong CS-Lewwin Drug Research Co., Ltd., Guangdong, CN;
Abstract
The present invention discloses a method of treating tumor using a novel pyrimidine derivative. It is demonstrated through the tests on anti-tumor activity at the cellular level (tumor cells expressed with c-Met) that, through the introduction of a chiral structure in the molecule, the introduction of an isotope of hydrogen (deuterium) at the sites that are prone to metabolism in the molecule, and the introduction of atoms or groups such as sulfur, selenium and sulfoxide in the molecule, the compounds of the invention have excellent anti-tumor activities, and the stabilities of the anti-tumor compounds are significantly improved.