The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
Feb. 02, 2024
Recode Therapeutics, Inc., Menlo Park, CA (US);
Mirko Hennig, Mountain View, CA (US);
Daniella Ishimaru, Menlo Park, CA (US);
David J. Lockhart, Menlo Park, CA (US);
Michael Torres, Menlo Park, CA (US);
Jackson Eby, Menlo Park, CA (US);
Dmitri Boudko, Menlo Park, CA (US);
Brandon A. Wustman, San Diego, CA (US);
ReCode Therapeutics, Inc., Menlo Park, CA (US);
Abstract
Compositions of polynucleotide(s), pharmaceutical compositions thereof, and methods of use thereof are disclosed. A polynucleotide may encode for a cystic fibrosis transmembrane conductance regulator (CFTR) protein or a functional fragment thereof. The polynucleotide may be assembled with a lipid composition for targeted delivery to a cell or an organ, such as a lung cell or a lung of a subject. Methods for enhancing an expression or activity of CFTR protein in a cell are provided. Methods for treating a subject having or suspected of having a CFTR-associated condition are also provided.