The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
May. 23, 2022
Applicant:
Novavax, Inc., Gaithersburg, MD (US);
Inventors:
Gale Smith, Germantown, MD (US);
Ye Liu, Clarksville, MD (US);
Jing-Hui Tian, Germantown, MD (US);
Michael J. Massare, Mt. Airy, MD (US);
Sarathi Boddapati, Germantown, MD (US);
Erica Shane, McLean, VA (US);
Cynthia Oliver, Potomac, MD (US);
Gregory Glenn, Poolesville, MD (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/155 (2013.01); A61K 9/0019 (2013.01); A61K 9/1611 (2013.01); A61K 9/1617 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55555 (2013.01); C12N 2710/14143 (2013.01); C12N 2760/14134 (2013.01); C12N 2760/14171 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16251 (2013.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01);
Abstract
Disclosed herein are nanoparticles suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.